COMET stands for Comparison of Operative to Monitoring and Endocrine Therapy for low-risk ductal carcinoma in situ (DCIS). This study will look at different management strategies for DCIS. It is the first national study in the United States (US) to do so. A randomized clinical trial will enroll 1200 women with low-risk DCIS. Enrollment will take place at about 100 cancer centers throughout the US. The study is funded by the Patient-Centered Outcomes Research Institute (PCORI).
The COMET study will look at two different interventions for DCIS:
- Standard care. This may include surgery (lumpectomy or mastectomy). It may also include radiation therapy.
- Active surveillance. This includes mammograms and physical exams every six months. Surgery is only recommended if needed.
In either group, you and your doctor will decide whether endocrine therapy is a good option.
Clinical Trial Categories
Tina Fortney, RN BSN, CCRC: 425.688.5407, Tina.Fortney@overlakehospital.org
Hania Shakalia, CRC, 424.635.6082, Hania.Shakalia@overlakehospital.org
Overlake Medical Center
1035 116th Ave. NE
Bellevue, WA 98004